MB7, strong memory T cell proliferation and inhibition of Treg cell proliferation
Enhanced anti-cancer efficacy is achievable through IL-21v tri-specific fusion protein via 1) proliferation of TCM and TEM cells, and 2) enhancement of TIL quality by inhibition of Treg cell proliferation mechanisms.
TEFF : Effector T cell; TCM : Central memmory T cell; TEM : Effector memory T cell